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Uveitis Uveitis is a complex ocular inflammatory disease that, without timely and thorough pharmacological treatment, can severely impact vision due to recurrences and associated complications [313]

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found that ROS depletion not only reduced ox-mtDNA production and the binding to NLRP3, but also prevented NLRP3 deubiquitinating, thereby suppressing NLRP3 inflammasome activation

5.1 Thyroid dysfunctions and OxS 5.1.1 Hypothyroidism Even in its subclinical form, hypothyroidism reduces antioxidant system activity, which promotes OxS, causing oxidative damage and altered lipid metabolism in thyroid cells (25, 46, 84)

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Transplanted senescent cells induce an osteoarthritis-like condition in mice